Yes. Both are considered to be safe and effective when used as indicated. But safe doesn’t mean that there aren’t risks. Both also carry a boxed warning about thyroid C-cell tumors occurring in rodents (with unknown risk in humans), and both shouldn’t be used if you or your family have a history of certain thyroid cancers. They should not be used in people with type-1 diabetes, history of pancreatitis or if you are pregnant. They should be used cautiously for people on other blood sugar lowering medications.